Xiaomei He, PhD. (Principal Investigator)
I obtained my B.S. degree in Chemistry from Xiamen University, and PhD. Degree in Analytical Chemistry from Wuhan University. In my graduate study, I mainly focused on developing adsorbent materials and enrichment methods for the identification of low-abundance protein modifications, including protein phosphorylation and glycosylation. After PhD graduation, I realized the importance of expanding my knowledge in biology to enhance my skill set further. Therefore, I joined Dr. Wang’s lab as a postdoc in the University of California Riverside. In Wang lab, I have gained a lot of experience in molecular and cell biology, and multi-omics approaches, including proteomics, bioinformatics and genomics.
Since 2024, I started my own research lab in ECU. My research interests involve in developing LC-MS/MS-based quantitative proteomics methods and bioinformatic prediction methods to identify novel protein-nucleic acid interactions and protein-protein interactions, as well as exploring the biological functions of these interactions in human cells. My work also entails employing an interdisciplinary approach, encompassing molecular and cell biology, next generation sequencing, quantitative proteomics, and bioinformatics to investigate novel crosstalks between RNA modifications and histone post-translational modifications.
Graduate Students
Junmin Chen, M.S. (PhD Student)
Interdisciplinary Doctoral Program in Biology, Biomedicine, and Chemistry (IDPBBC)
Research Interest: Chemical Biology of U2AF1
Undergraduate Students
Debbie Le
Honors College 2027
Research Interest: Investigating how disease-related mutations in U2AF1 affect U2AF1-R-loop interaction
Isaiah Proctor
Biology 2025
Research Interest: Examining the biological function of DHX9 in the nucleolus
Former Lab Members
Lawrence Meshaun Newkirk, B.S.
Caroline Marie Johnston, B.S.
Shyla Soto, B.S.
Recruitment
I am seeking highly motivated undergraduate and graduate students who are enthusiastic about my research to join the lab. If you are interested, please email me at hex24@ecu.edu with your CV or resume along with a brief statement of your research interests and career goals.